Biosistemas e Ingeniería de Bioprocesos
Desde el modelado matemático y la simulación por ordenador hasta el diseño, control y optimización de bioprocesos y sistemas biológicos.
El mundo que nos rodea puede explicarse en gran medida entendiendo los sistemas que lo componen y los procesos que los conectan.
El Grupo de Biosistemas e Ingenieria de Bioprocesos del IIM-CSIC trabaja para desarrollar nuevos métodos y herramientas (fundamentalmente software) orientados a la ingeniería de sistemas de procesos que permitan la simulación, optimización y control de bioprocesos, tales como los implicados en el procesado y la conservación de alimentos y en la biotecnología industrial.
El grupo aplica métodos de ingenería de sistemas de procesos para mejorar la eficiencia de procesos industriales clave, reduciendo así su impacto medioambiental y mejorando la calidad y seguridad de sus productos.
El objetivo de su estudio es la identificación de modelos y la optimización, monitorización y control robusto de los sistemas dinámicos no lineales, incluidos los sistemas de parámetros distribuidos (convección-difusión-reacción). El grupo contempla un amplio espectro de aplicaciones, fundamentalmente la gestión de pesquerías, el procesado, la calidad y la seguridad de los alimentos (incluida la resistencia a agentes antimicrobianos) y la biotecnología industrial.
Ari Salvador Moreno Razo
Artai Rodriguez Moimenta
Carlos Vilas Fernandez
Eva Maria Balsa Canto
Helena Nina Del Rio Ares
Juan Carlos Ovalle Macias
Luis Taboada Antelo
Miriam Rodriguez Garcia
Oana-Teodora Chis
Saeed Salehi
Vicente Dominguez Arca
Aplicabilidad de la tecnología de imágenes hiperespectrales (HSI) como método no invasivo para la evaluación de la calidad del pescado
TFM – Andrea Arribas Jimeno (26/09/2022) Aplicabilidad de la tecnología de imágenes hiperespectrales (HSI) como método no invasivo para la evaluación de la calidad del pescado UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
Kinetics of Bacterial Adaptation, Growth, and Death at Didecyldimethylammonium Chloride sub-MIC Concentrations
Pedreira, A.; Vázquez, J.A.; García, M.R. (2022) Kinetics of Bacterial Adaptation, Growth, and Death at Didecyldimethylammonium Chloride sub-MIC Concentrations Frontiers in Microbiology DOI:10.3389/fmicb.2022.758237
Las nuevas tecnologías y la interdisciplinariedad marcan el rumbo de la ciencia pesquera
Alexandre Alonso Fernández; Laura Casas Castaño; Luis Taboada Antelo; Jaime Amaro Blanco; Fran Saborido Rey (2021) Las nuevas tecnologías y la interdisciplinariedad marcan el rumbo de la ciencia pesquera Industrias Pesqueras
Challenge 9: Towards an ocean-engaged society
José Pintado Valverde; Ana Crespo Solana; Eva Balsa Canto; Elisa Berdalet; Salvador Bernabeu Albert; Albert Calbet; Arnaud Cazenave de la Roche; Juan Francisco Gibaja Bao; Xavier García; Eulàlia Gracia Mont; Elías López-Romero; Manuel Lucena Giraldo; M. Pilar Martín; Luisa Martínez Lorenzo; Javier Martínez-Vega; Consuelo Naranjo Orovio; Gabriela Ojeda-Romano; Estrella Olmedo; José Luis Oviedo; Ananda Pascual; Jaume Piera; Juan Pimentel; Miguel-Ángel Puig Samper; Miguel Ángel Rodríguez Arias; Valentí Sallarés; Cristina Sánchez-Carretero; Karen Soacha; Joaquín Tintoré Subirana (2021) Challenge 9: Towards an ocean-engaged society » Ocean Science Challenges For 2030″ Consejo Superior de Investigaciones Científicas ISBN:978-84-00-10762-8
The Monod Model Is Insufficient To Explain Biomass Growth in Nitrogen-Limited Yeast Fermentation
Henriques, D.; Balsa-Canto, E. (2021) The Monod Model Is Insufficient To Explain Biomass Growth in Nitrogen-Limited Yeast Fermentation Applied and Environmental Microbiology DOI:10.1128/AEM.01084-21
Eco-efficiency of a marine biorefinery for valorization of cartilaginous fish biomass
García-Santiago, X.; Franco-Uría, A.; Antelo, L.T.; Vázquez, J.A.; Pérez-Martín, R.; Moreira, M.T.; Feijoo, G. (2021) Eco-efficiency of a marine biorefinery for valorization of cartilaginous fish biomass Journal of Industrial Ecology DOI:10.1111/jiec.13066
Assessing the impact of bivalve aquaculture on the carbon circular economy
Alonso, A.A.; Álvarez-Salgado, X.A.; Antelo, L.T. (2021) Assessing the impact of bivalve aquaculture on the carbon circular economy Journal of Cleaner Production DOI:10.1016/j.jclepro.2020.123873
A multiphase multiobjective dynamic genome-scale model shows different redox balancing among yeast species of the saccharomyces genus in fermentation
Henriques, D.; Minebois, R.; Mendoza, S.N.; Macías, L.G.; Pérez-Torrado, R.; Barrio, E.; Teusink, B.; Querol, A.; Balsa-Canto, E. (2021) A multiphase multiobjective dynamic genome-scale model shows different redox balancing among yeast species of the saccharomyces genus in fermentation mSystems DOI:10.1128/mSystems.00260-21
Innovative marine technologies applied to discard mitigation and management: The MARTEC18 conference
Luis T. Antelo; Jose M. Bellido; Julio Valeiras; Ricardo I. Pérez-Martín (2020) Innovative marine technologies applied to discard mitigation and management: The MARTEC18 conference Marine Policy DOI:10.1016/j.marpol.2020.103911
Valorisation of fish discards assisted by enzymatic hydrolysis and microbial bioconversion: Lab and pilot plant studies and preliminary sustainability evaluation
Vázquez, J.A.; Fraguas, J.; Mirón, J.; Valcárcel, J.; Pérez-Martín, R.I.; Antelo, L.T. (2020) Valorisation of fish discards assisted by enzymatic hydrolysis and microbial bioconversion: Lab and pilot plant studies and preliminary sustainability evaluation Journal of Cleaner Production DOI:10.1016/j.jclepro.2019.119027
Use of computer vision onboard fishing vessels to quantify catches: The iObserver
Vilas, C.; Antelo, L.T.; Martin-Rodriguez, F.; Morales, X.; Perez-Martin, R.I.; Alonso, A.A.; Valeiras, J.; Abad, E.; Quinzan, M.; Barral-Martinez, M. (2020) Use of computer vision onboard fishing vessels to quantify catches: The iObserver Marine Policy DOI:10.1016/j.marpol.2019.103714
Marine chondroitin sulfate of defined molecular weight by enzymatic depolymerization
Valcarcel, J.; García, M.R.; Sampayo, L.F.; Vázquez, J.A. (2020) Marine chondroitin sulfate of defined molecular weight by enzymatic depolymerization Carbohydrate Polymers DOI:10.1016/j.carbpol.2019.115450
Hyaluronic acid of tailored molecular weight by enzymatic and acid depolymerization
Valcarcel, J.; García, M.R.; Varela, U.R.; Vázquez, J.A. (2020) Hyaluronic acid of tailored molecular weight by enzymatic and acid depolymerization International Journal of Biological Macromolecules DOI:10.1016/j.ijbiomac.2019.12.221
Environmental Implications of Discarding Fish in Northern Spanish Coastal Bottom Otter Trawl Fisheries
García-Santiago, X.; Franco-Uría, A.; Antelo, L.T.; Moreira, M.T.; Feijoo, G.; Pérez-Martín, R.I. (2020) Environmental Implications of Discarding Fish in Northern Spanish Coastal Bottom Otter Trawl Fisheries Fisheries DOI:10.1002/fsh.10429
An on-land management and valorisation approach for biomass associated with landing obligation compliance
Pérez-Martín, R.I.; Antelo, L.T.; Vázquez, J.A.; Mirón, J. (2020) An on-land management and valorisation approach for biomass associated with landing obligation compliance Marine Policy DOI:10.1016/j.marpol.2019.04.010
Tools and Technologies for the Monitoring, Control and Surveillance of Unwanted Catches
James K.M; Campbell, N; Vidarsson, J.R; Vilas, C; Plet-Hansen, K.S; Borges, Lisa; González, O; van Helmong, A.T.M; Pérez-Martín, R.I.; Taboada Antelo, L; Pérez-Bouzada, J (2019) Tools and Technologies for the Monitoring, Control and Surveillance of Unwanted Catches » The European Landing Obligation» Springer ISBN:978-3-030-03308-8
What to Do with Unwanted Catches: Valorisation Options and Selection Strategies
Iñarra B., Bald, C; Cebrián, M; Antelo, L.T.; Franco-Uría, A.; Vázquez, J.A; Pérez-Martín, R.I.; Zufía, J (2019) What to Do with Unwanted Catches: Valorisation Options and Selection Strategies » The European Landing Obligation» Springer ISBN:978-3-030-03308-8
Stochastic individual-based modeling of bacterial growth and division using flow cytometry
García, M.R.; Vázquez, J.A.; Teixeira, I.G.; Alonso, A.A. (2018) Stochastic individual-based modeling of bacterial growth and division using flow cytometry Frontiers in Microbiology DOI:10.3389/fmicb.2017.02626
Saccharomyces cerevisiae and S. kudriavzevii synthetic wine fermentation performance dissected by predictive modeling
Henriques, D.; Alonso-del-Real, J.; Querol, A.; Balsa-Canto, E. (2018) Saccharomyces cerevisiae and S. kudriavzevii synthetic wine fermentation performance dissected by predictive modeling Frontiers in Microbiology DOI:10.3389/fmicb.2018.00088
Optimization of E. coli inactivation by benzalkonium chloride reveals the importance of quantifying the inoculum effect on chemical disinfection
García, M.R.; Cabo, M.L. (2018) Optimization of E. coli inactivation by benzalkonium chloride reveals the importance of quantifying the inoculum effect on chemical disinfection Frontiers in Microbiology DOI:10.3389/fmicb.2018.01259
Isolation and chemical characterization of chondroitin sulfate from cartilage by-products of blackmouth catshark (Galeus melastomus)
Vázquez, J.A.; Fraguas, J.; Novoa-Carvallal, R.; Reis, R.L.; Antelo, L.T.; Pérez-Martín, R.I.; Valcarcel, J. (2018) Isolation and chemical characterization of chondroitin sulfate from cartilage by-products of blackmouth catshark (Galeus melastomus) Marine Drugs DOI:10.3390/md16100344
Chitin production from crustacean biomass: Sustainability assessment of chemical and enzymatic processes
Lopes, C.; Antelo, L.T.; Franco-Uría, A.; Alonso, A.A.; Pérez-Martín, R. (2018) Chitin production from crustacean biomass: Sustainability assessment of chemical and enzymatic processes Journal of Cleaner Production DOI:10.1016/j.jclepro.2017.01.082
A mathematical model to predict early quality attributes in hake during storage at low temperature
Vilas, C.; Alonso, A.A.; Herrera, J.R.; Bernárdez, M.; García, M.R. (2018) A mathematical model to predict early quality attributes in hake during storage at low temperature Journal of Food Engineering DOI:10.1016/j.jfoodeng.2017.11.005
An integral and sustainable valorisation strategy of squid pen by-products
Vázquez, J.A.; Ramos, P.; Valcarcel, J.; Antelo, L.T.; Novoa-Carballal, R.; Reis, R.L.; Pérez-Martín, R.I. (2018) An integral and sustainable valorisation strategy of squid pen by-products Journal of Cleaner Production DOI:10.1016/j.jclepro.2018.07.316
Smart sensor to predict retail fresh fish quality under ice storage
García, M.R.; Cabo, M.L.; Herrera, J.R.; Ramilo-Fernández, G.; Alonso, A.A.; Balsa-Canto, E. (2017) Smart sensor to predict retail fresh fish quality under ice storage Journal of Food Engineering DOI:10.1016/j.jfoodeng.2016.11.006
Modeling reveals the role of aging and glucose uptake impairment in L1A1 Listeria monocytogenes biofilm life cycle
Balsa-Canto, E.; Vilas, C.; López-Núñez, A.; Mosquera-Fernández, M.; Briandet, R.; Cabo, M.L.; Vázquez, C. (2017) Modeling reveals the role of aging and glucose uptake impairment in L1A1 Listeria monocytogenes biofilm life cycle Frontiers in Microbiology DOI:10.3389/fmicb.2017.02118
Data-driven reverse engineering of signaling pathways using ensembles of dynamic models
Henriques, D.; Villaverde, A.F.; Rocha, M.; Saez-Rodriguez, J.; Banga, J.R. (2017) Data-driven reverse engineering of signaling pathways using ensembles of dynamic models PLoS Computational Biology DOI:10.1371/journal.pcbi.1005379
A parallel metaheuristic for large mixed-integer dynamic optimization problems, with applications in computational biology
Penas, D.R.; Henriques, D.; González, P.; Doallo, R.; Saez-Rodriguez, J.; Banga, J.R. (2017) A parallel metaheuristic for large mixed-integer dynamic optimization problems, with applications in computational biology PLoS ONE DOI:10.1371/journal.pone.0182186
A model for the biochemical degradation of inosine monophosphate in hake (Merluccius merluccius)
Vilas, C.; Alonso, A.A.; Herrera, J.R.; García-Blanco, A.; García, M.R. (2017) A model for the biochemical degradation of inosine monophosphate in hake (Merluccius merluccius) Journal of Food Engineering DOI:10.1016/j.jfoodeng.2016.12.016
Caracterización numérica de la dinámica espacio-temporal de biopelículas bacterianas de Listeria monocytogenes
PhD – Maruxa Mosquera Fernández (02/11/2016) Caracterización numérica de la dinámica espacio-temporal de biopelículas bacterianas de Listeria monocytogenes Universidade de Vigo (UVIGO)
SYNBADm: A tool for optimization-based automated design of synthetic gene circuits
Otero-Muras, I.; Henriques, D.; Banga, J.R. (2016) SYNBADm: A tool for optimization-based automated design of synthetic gene circuits Bioinformatics DOI:10.1093/bioinformatics/btw415
Quantitative image analysis to characterize the dynamics of Listeria monocytogenes biofilms
Mosquera-Fernández, M.; Sanchez-Vizuete, P.; Briandet, R.; Cabo, M.L.; Balsa-Canto, E. (2016) Quantitative image analysis to characterize the dynamics of Listeria monocytogenes biofilms International journal of food microbiology DOI:10.1016/j.ijfoodmicro.2016.07.015
Pollutant levels in discarded fish species by Spanish trawlers operating in the Great Sole Bank and the Atlantic coast of the Iberian Peninsula
Antelo, L.T.; Ordóñez-del Pazo, T.; Lopes, C.; Franco-Uría, A.; Pérez-Martín, R.I.; Alonso, A.A. (2016) Pollutant levels in discarded fish species by Spanish trawlers operating in the Great Sole Bank and the Atlantic coast of the Iberian Peninsula Marine Pollution Bulletin DOI:10.1016/j.marpolbul.2016.04.040
AMIGO2, a toolbox for dynamic modeling, optimization and control in systems biology
Balsa-Canto, E.; Henriques, D.; Gábor, A.; Banga, J.R. (2016) AMIGO2, a toolbox for dynamic modeling, optimization and control in systems biology Bioinformatics DOI:10.1093/bioinformatics/btw411
Caracterización numérica de la evolución de la estructura espacial de biopelículas
TFM – Maruxa Mosquera Fernández (07/02/2012) Caracterización numérica de la evolución de la estructura espacial de biopelículas UNIVERSIDAD DE VIGO