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Research group

Immunology and Genomics

Description

Deepening our understanding of processes related to diseases, immune systems and gene expression in marine organisms is essential for the development of a more sustainable and profitable aquaculture sector.

It can also provide society with a broad body of knowledge and a set of technologies that may even have an impact on human health. 

The studies carried out by the Immunology and Genomics group at IIM-CSIC focus on the molecular basis of the immune response to pathogens in aquaculture fish and mollusks, their transcriptomics and proteomics, paying special attention to innate immune responses in these organisms and to their potential biotechnological applications in animal and human health, as well as in the optimization of aquaculture processes.

The group seeks to identify genes that can be used as biomarkers in genetic selection processes, as well as to improve immune response through the use of immunostimulants and vaccines. Its main research focus is the key mechanisms of the innate immune response, such as antimicrobial peptides (AMPs), inflammatory processes related to cytokines and antiviral and antibacterial activities. To study these mechanisms, the group uses immunological, microbiological, molecular biology and protein biochemistry techniques. The use of zebrafish (Danio rerio) to study both fish and human diseases is also a main feature of the group's research work.

In collaboration with other scientific and technological services (see below), the group is responsible for the National Reference Laboratory for Bivalve Mollusc Diseases (LNREMB), which carries out its work within this research group. In 2011, it received accreditation under the ISO 17025 standard for several diagnostic techniques for pathogens in mollusks. This service reports directly to the Ministry of Agriculture, Fisheries and Food (MAPA).

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Publications