Biotechnology
Biotechnology is experiencing a rapid acceleration thanks to the advances in omic techniques and computing capacities, which allow us to better understand how we can put nature’s machinery to use for the good of humanity. Biotechnology is a broad discipline in which biological processes, cells or organisms are exploited to develop new technologies, with applications in agri- and aquaculture, food production, industrial processes and medicine.
Because of this wide range of applications, biotechnology is usually color-coded to refer to its four main fields of application. Industrial biotechnology is usually referred to as white biotechnology, while red is reserved for medical applications, green for agriculture-related developments, and blue for processes that encompass the aquatic environment.
The interdisciplinary nature of the IIM-CSIC allows us to collaborate with different industries for the application of biotechnological innovations across the whole color range of biotechnology.
You can read about all our capabilities and associated services below.
Capabilities
- Software | Model-based design of smart active packaging systems with antimicrobial activity
Matlab code to perform simulations and optimize packaging design using natural antimicrobials (carvacrol) for hake (Merluccius merluccius). In addition, different polymers are considered as possible active packaging materials.
More information here.
- Capabilities | Advanced -omics applied to marine organisms
Studies on the structure of the genome of marine organisms, including gene mapping, DNA sequencing and how the complete set of RNA transcripts is produced by the genome and affected by development, diseases, or environmental factors conditioning the phenotype and particularly proteomics and metabolomics, always applying the most advanced techniques (ATAC-seq, MethylCap-Seq, RNA-seq, recombinant DNA technology, knockin and knockout CRISPR/Cas9, enhancer detector (ZED),Tol2 kit and BAC transgenic technologies, etc.).
- Software | Kinetics of E. coli inactivation by benzalkonium chloride v1.0
This model and associated code was developed to optimize disinfection protocols and minimize bacterial resistance. This model was applied in the following journal article: Optimization of E. coli Inactivation by Benzalkonium Chloride Reveals the Importance of Quantifying the Inoculum Effect on Chemical Disinfection. Front. Microbiol., 26 June 2018. https://doi.org/10.3389/fmicb.2018.01259
More information and access to the code here.
- Capabilities | Development of pathogen-resistant variants for aquaculture
Application of the most advanced -omic techniques for the identification of resistance genes that can be used as biomarkers for the selection of pathogen-resistant variants of marine aquaculture species.
- Software | saCeSS: a parallel global optimization library
The saCeSS library allows solving non-linear programming (NLP) and mixed-integer non-linear programming (MINLP) problems. It also offers efficient local solvers for nonlinear parameter estimation problems associated with complex models (e.g. those described by differential equations).
More information here.
Active projects
- LIFE REFISH -
<p>Flexible biorefinery to valorise discards and by-products of the European fish and seafood production (REFISH)</p>
Principal investigator:VázquezÁlvarezXosé AntónFunding body:LIFE Environment (Nature & Circular Economy)Funding for IIM-CSIC:357637€Fromto - PESCANDO 4.0 -
<p>Plataforma Blockchain e IoT para garantizar la trazabilidad, seguridad, calidad y sostenibilidad en la cadena de valor de los productos pesqueros</p>
Principal investigator:VilasFernándezCarlosFunding body:PROYECTO FINANCIADO POR EL PLAN DE RECUPERACIÓN, TRANSFORMACIÓN Y RESILIENCIA Y LOS FONDOS EUROPEOS NEXT GENERATION EU EN EL MARCO DEL REAL DECRETO 685/2021 DEL 3 DE AGOSTOFunding for IIM-CSIC:145812€Fromto - METDISHFISH -
<p>Terapias metabólicas para el tratamiento de enfermedades infecciosas en peces de cultivo</p>
Principal investigator:NovoaGarcíaBeatrizFunding body:Ayuda cofinanciada por el Fondo Europeo Marítimo y de Pesca y el Ministerio de Agricultura, Pesca y Alimentación.Funding for IIM-CSIC:324175€Fromto - BIOTRANSFER -
<p>Polymicrobial L. monocytogenes-carrying biofilms as a key on the risk of listeriosis in foods</p>
Principal investigator:LópezCaboMartaFunding body:CSICFunding for IIM-CSIC:28557€Fromto - VALOR -
<p>Valorización integral de los efluentes y residuos de pieles generados en el proceso de producción de gelatinas marinas de alta calidad</p>
Principal investigator:VázquezÁlvarezXosé AntónFunding body:CSICFunding for IIM-CSIC:21600€Fromto - DTWINE2021 -
<p>Digital Twins to optimize energy efficiency and product quality in WINEries</p>
Principal investigator:BalsaCantoEvaFunding body:Proyecto PLEC2021-007827 financiado por MCIN/ AEI /10.13039/501100011033 y por la Unión Europea NextGenerationEU/PRTRFunding for IIM-CSIC:248164€Fromto - SEAFOOD-ID -
<p>ANALYTICAL STRATEGIES BASED ON NON-DESTRUCTIVE METHODS AND METAGENOMICS FOR THE CONTROL OF PRODUCTION METHOD AND GEOGRAPHIC ORIGIN</p>
Principal investigator:GonzálezSoteloCarmenPérezMartínRicardo IsaacFunding body:Proyecto PID2020-118012RB-C21 financiado por MCIN/ AEI /10.13039/501100011033Funding for IIM-CSIC:168000€Fromto - IMANREFIVIR -
<p>IMMUNE ANTIVIRAL RESPONSE OF FISH AGAINST RNA VIRUSES</p>
Principal investigator:NovoaGarcíaBeatrizFunding body:Proyecto PID2020-119532RB-I00 financiado por MCIN/ AEI /10.13039/501100011033Funding for IIM-CSIC:160000€Fromto - Contrato Programa -
<p>AYUDA CONVENIO ENTRE CSIC Y LA AXENCIA GALEGA DE INNOVACIÓN -GAIN- PARA EL DESARROLLO DE PROGRAMAS DE I+D+i EN LOS INSTITUTOS DE INVESTIGACIÓN DEL CSIC EN GALICIA Y EN LOS CENTROS OCEANOGRÁFICOS DEL INSTITUTO ESPAÑOL DE OCEANOGRAFÍA (CSIC-IEO). 2021-2022</p>
Principal investigator:SaboridoReyFranFunding body:Agencia Galega de InnovaciónFunding for IIM-CSIC:521824€Fromto - ISEAS -
<p>Nanopartículas con hidrolizados de colágeno marino: aplicaciones en cosmética</p>
Principal investigator:PérezMartínRicardo IsaacFunding body:CSICFunding for IIM-CSIC:52000€Fromto